PromaCare-PO / Piroctone Olamine

Short Description:

The only antidandruff agent and antipruritic that can be used in leave-on hair products. Widely used in body wash, have superior function of relieving itching;Have sterilization and deodorization effects; Have broad-spectrum killing effect on fungus and mould, have great treatment efficacy ontinea manuum and tinea pedis.Can be used as preservatives in cosmetics and bactericide as well as thickeners in soap.

Product Detail

Product Tags

Product Paramete

Trade name PromaCare-PO
CAS No. 68890-66-4
INCI Name Piroctone Olamine
Chemical Structure
Application Soap,body wash,shampoo
Package 25kgs net per fiber drum
Appearance White crystalline powder
Assay 98.0-101.5%
Solubility Oil soluble
Function Hair care
Shelf life 1 year
Storage Keep container tightly closed and in a cool place. Keep away from heat.
Dosage 0.5% max


PromaCare-PO is famous for its antibacterial activity, especially for its ability to inhibit Plasmodium ovale, which parasitizes in dandruff and face dandruff.

It is usually used instead of zinc pyridyl thioketone in shampoo. It has been used in personal care products for more than 30 years. It is also used as preservative and thickener. Piloctone olamine is an ethanolamine salt of pyrrolidone hydroxamic acid derivative.

Dandruff and seborrheic dermatitis are the causes of hair loss and thinning. In a controlled clinical trial, the results showed that piloctone olamine was superior to ketoconazole and zinc pyridyl thioketone in the treatment of androgen induced alopecia by improving hair core, and piloctone olamine could reduce oil secretion.


pH: Stable in solution of pH 3 to pH 9.

Heat: Stable to heat, and to short time of high temperature above 80℃. Piroctone olamine in shampoo of pH 5.5-7.0 remains stable after one year of storage at a temperature over 40℃.

Light: Decompose under direct ultraviolet radiation. So it should be protected from light.

Metals: An aqueous solution of piroctone olamine degrades in the presence of cupric and ferric ions.


Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water or in 1%-10% ethanol; slightly soluble in water and in oil. The solubility in water varies by pH value, and is a litter larger in neutral or weak basic solution than in acid solution.

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