| Brand name | ActiTide-PT7 |
| CAS No. | 221227-05-0 |
| INCI Name | Palmitoyl Tetrapeptide-7 |
| Application | Lotion, Serums, Mask, Facial cleanser |
| Package | 100g/bottle |
| Appearance | White to off-white powder |
| Solubility | Insoluble in water |
| Function | Peptide series |
| Shelf life | 2 years |
| Storage | Store the container tightly closed in a cool, dry place at 2 - 8°C. |
| Dosage | 0.001-0.1% below 45 °C |
Application
ActiTide-PT7 is an active peptide that mimics a fragment of immunoglobulin IgG. Modified with palmitoylation, it exhibits enhanced stability and transdermal absorption capacity, enabling more effective penetration into the skin to exert its function.
Core Mechanism of Action: Regulating Inflammation:
Targeting Key Factor: Its core mechanism lies in significantly reducing the production of the pro-inflammatory cytokine Interleukin-6 (IL-6).
Alleviating Inflammatory Response: IL-6 is a key mediator in skin inflammatory processes. High concentrations of IL-6 exacerbate inflammation, accelerate the breakdown of collagen and other important skin structural proteins, thereby promoting skin aging. Palmitoyl Tetrapeptide-7 acts on skin keratinocytes and fibroblasts through signal stimulation, regulating inflammatory responses, particularly by inhibiting the excessive release of IL-6 from white blood cells.
Dose-Dependent Inhibition: Laboratory studies confirm it inhibits IL-6 production in a dose-dependent manner; higher concentrations yield more significant inhibitory effects (up to 40% maximum inhibition rate).
Highly Effective Against Photo-Damage: In cases where ultraviolet (UV) radiation induces massive IL-6 production, cells treated with Palmitoyl Tetrapeptide-7 show an inhibition rate of IL-6 production up to 86%.
Primary Efficacy and Benefits:
Soothes and Reduces Inflammation: By effectively inhibiting inflammatory factors like IL-6, it alleviates inappropriate skin inflammatory reactions, reducing redness and discomfort.
Protects Against Environmental Damage: Helps maintain the balance of skin cytokines, protecting the skin from environmental damage (such as UV radiation) and glycation damage.
Promotes Even Skin Tone: Reducing inflammation helps improve skin redness and other uneven tone issues, potentially helping to brighten the complexion for a more even skin tone.
Delays Signs of Aging: By reducing inflammation and preventing collagen breakdown, it helps combat aging signs such as wrinkles and sagging.
Synergistic Enhancement: When combined with other active ingredients (such as Palmitoyl Tripeptide-1), for example in the Matrixyl 3000 complex, it produces synergistic effects, enhancing overall anti-aging results.
Application:
ActiTide-PT7 is widely used in skincare products, particularly playing an important role in skin repair, anti-inflammatory soothing, and anti-wrinkle firming products.
