ActiTide-NP1 / Nonapeptide-1

Short Description:

Alpha-Melanocyte-Stimulating Hormone (α-MSH), a 13-amino acid peptide, binds to its receptor (MC1R) to activate the melanin pathway, resulting in increased melanin production and darker skin. ActiTide-NP1, a biomimetic peptide designed to mimic the sequence of α-MSH, competitively inhibits the binding of α-MSH to its receptor. By blocking the activation of the melanin pathway at its source, ActiTide-NP1 reduces melanin synthesis and exhibits skin-brightening efficacy.


Product Detail

Product Tags

Brand name ActiTide-NP1
CAS No. /
INCI Name Nonapeptide-1
Application Mask series, Cream series, Serum series
Package 100g/bottle, 1kg/bag
Appearance White to off-white powder
Peptide content 80.0 min
Solubility Soluble in water
Function Peptide series
Shelf life 2 year
Storage Should be stored at 2~8°C in a tightly closed container
Dosage 0.005%-0.05%

Application

1. Blocks the binding of α – MSH with its receptor MC1R on the cell membrane of melanocyte. The successive melanin – producing process is stopped.
2. A whitening agent that works on the very initial stage of the skin – darkening mechanism. Highly efficacious.
Prevents further activation of tyrosinase and thus blocks melanin synthesis for better control over skin tone and brown spots.
3. Prevents hyper – production of melanin.

To avoid prolonged exposure to high temperatures, it is recommended to add ActiTide-NP1 in the final stage of the formulation, at a temperature below 40 °C.

Cosmetic benefits:

ActiTide-NP1 can be incorporated in: Skin radiance / Skin lightening – whitening / Anti – dark spot formulations.


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