PromaEssence-MDC (90%) / Madecassoside

PromaEssence-MDC (90%) / Madecassoside Featured Image
  • PromaEssence-MDC (90%) / Madecassoside

Short Description:

PromaEssence-MDC (90%) is one of the core active ingredients of centella asiatica extract. It has excellent effects in the field of skin care and is known as “nature’s repair miracle”: it can accelerate skin repair by promoting collagen synthesis, effectively fade scars, and achieve skin base regeneration; at the same time, PromaEssence-MDC (90%) has excellent soothing and repairing abilities, can relieve skin sensitivity, and strengthen barrier function, and is especially suitable for the care of fragile skin; it also has multiple anti-oxidation and anti-aging effects, which can not only remove free radicals, but also fade fine lines, enhance elasticity, and restore the skin to a firm, delicate, and youthful state.


Product Detail

Product Tags

Brand name: PromaEssence-MDC (90%)
CAS No.: 34540-22-2
INCI Name: Madecassoside
Application: Creams; Lotions; Masks
Package: 1kg/bag
Appearance: Crystal powder
Function: Anti-aging and antioxidant; Soothing and repairing; Moisturizing and firming
Shelf life: 2 years
Storage: Store the container tightly closed in a dry, cool and well-ventilated place.
Dosage: 2-5%

Application

Repair & Regeneration
PromaEssence-MDC (90%) significantly upregulates the gene expression and protein synthesis of Type I and Type III collagen, accelerates fibroblast migration, shortens wound healing time, and enhances the mechanical tension of newly formed skin. By scavenging free radicals, elevating glutathione levels, and increasing hydroxyproline content, it effectively mitigates oxidative stress damage to the skin.

Anti-inflammatory & Soothing
It inhibits the IL-1β inflammatory pathway induced by Propionibacterium acnes, alleviating acute inflammatory reactions such as redness, swelling, heat, and pain. It is a core active ingredient traditionally used for skin damage and dermatitis.

Moisturizing Barrier
It bilaterally enhances the skin’s moisturizing system: on one hand, by upregulating aquaporin-3 (AQP-3) expression to boost the active transport capacity of water and glycerol in keratinocytes; on the other hand, by increasing the content of ceramides and filaggrin in the cornified envelope, thereby reducing transepidermal water loss (TEWL) and restoring barrier integrity.

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