| Brand name: | PromaCare R-PDRN |
| CAS No.: | / |
| INCI Name: | Sodium DNA |
| Application: | Mid-to high-end cosmetic lotions, creams, eye patches, masks, etc |
| Package: | 50g |
| Appearance: | White powder |
| Product grade: | Cosmetic grade |
| Solubility: | Soluble in water |
| pH (1% aqueous solution): | 5.0 -9.0 |
| Shelf life | 2 years |
| Storage: |
Keep in a cool place away from sunlight at room temperature |
| Dosage: |
0.01%-3.33% |
Application
R&D Background:
Traditional PDRN is primarily extracted from salmon testicular tissue. Due to variations in technical expertise among manufacturers, the process is not only costly and unstable but also struggles to guarantee product purity and batch-to-batch consistency. Moreover, excessive reliance on natural resources places significant pressure on the ecological environment and fails to meet the enormous future market demand.
The synthesis of salmon-derived PDRN via a biotechnological pathway successfully bypasses the limitations of biological extraction. This approach not only enhances production efficiency but also eliminates dependence on biological resources. It addresses quality fluctuations caused by contamination or impurities during extraction, achieving a quantum leap in component purity, efficacy consistency, and production controllability, thereby ensuring stable and scalable manufacturing.
Technical Advantages:
1. 100% Precisely Designed Functional Sequence
Achieves precise replication of the target sequence, constructing truly “efficacy-designed” customized nucleic acid products.
2. Molecular Weight Consistency and Structural Standardization
Controlled fragment length and sequence structure significantly enhance molecular fragment homogeneity and transdermal performance.
3. Zero Animal-Derived Components, Aligning with Global Regulatory Trends
Increases market acceptance in sensitive application areas.
4. Sustainable and Scalable Global Production Capacity.
Independent of natural resources, enables unlimited scalability and stable global supply through GMP-compliant fermentation and purification processes, comprehensively addressing the three major challenges of traditional PDRN: cost, supply chain, and environmental sustainability.
PromaCare R-PDRN raw material perfectly aligns with the green and sustainable development needs of mid-to-high-end brands.
Efficacy and Safety Data:
1. Significantly Promotes Repair and Regeneration: In vitro experiments demonstrate that the product significantly enhances cell migration ability, exhibits superior efficacy in promoting collagen production compared to traditional PDRN, and delivers more pronounced anti-wrinkle and firming effects.
2. Anti-Inflammatory Efficacy: It effectively inhibits the release of key inflammatory factors (e.g., TNF-α, IL-6).
3. Exceptional Synergistic Potential: When combined with sodium hyaluronate (concentration: 50 μg/mL each), the cell migration rate can increase by up to 93% within 24 hours, demonstrating excellent potential for combination applications.
4. Safe Concentration Range: In vitro studies indicate that 100-200 μg/mL is a universally safe and effective concentration range, balancing both pro-proliferative (peak effect at 48-72 hours) and anti-inflammatory activities.
