| Brand name: | PromaCare-PDRN |
| CAS No.: | / |
| INCI Name: | Sodium DNA |
| Application: | Repairing series product; Anti-aging series product; Brightening series product |
| Package: | 20g/bottle, 50g/bottle or according to customer needs |
| Appearance: | White, white-like or light yellow powder |
| Solubility: | Soluble in water |
| pH (1% aqueous solution): | 5.0 – 9.0 |
| Shelf life: | 2 years |
| Storage: | Store the container tightly closed in a dry, cool and well-ventilated place. |
| Dosage: | 0.01 – 2% |
Application
PDRN is a mixture of deoxyribonucleic acid present in human placenta, which is one of the complexes that generate DNA raw materials in cells. With its special ability to promote recovery after skin grafting, PDRN was first used as a tissue repair compound in Italy after its approval in 2008. In recent years, PDRN Mesotherapy has become one of the hottest technologies in Korean skin clinics and plastic surgery due to its miraculous efficacy in aesthetics. As a kind of cosmetic and pharmaceutical raw material, PromaCare-PDRN is widely used in medical cosmetology, daily chemical products, medical devices, health food, medicine and other fields. PDRN (polydeoxyribonucleotides) is a polymer of deoxyribonucleic acid extracted by a rigorous purification process with high safety and stability.
PromaCare-PDRN binding to the adenosine A2A receptor initiates multiple signaling pathways that regulate the release of inflammatory factors and inflammation. The specific mechanism is firstly to promote the proliferation of fibroblasts and the secretion of EGF, FGF, IGF, to remodel the internal environment of damaged skin. Secondly, PromaCare-PDRN can promote the release of VEGF to help capillary generation and supply the nutrients needed for skin repair and discharging aging substances. In addition, PDRN provides purines or pyrimidines through the salvage pathway that accelerates DNA synthesis enabling rapid skin regeneration.
