Protesse G66: Advancing Gentle Exfoliation and Long-Lasting Hydration in Skincare

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In the evolving landscape of functional skincare, Protesse G66 is emerging as a cutting-edge solution that combines gentle exfoliation with sustained moisturizing benefits. Developed with an encapsulated papain system and sclerotium gum-based sustained release technology, Protesse G66 ensures enzyme stability, compatibility, and controlled delivery within cosmetic formulations.

Innovative Technology for Stable and Gentle Performance
Protesse G66 utilizes a proprietary “4D” approach—integrating three-dimensional spatial arrangement and time-controlled release—to protect papain’s enzymatic activity while enhancing its compatibility with formulations. The encapsulation reduces direct contact with environmental factors, improving papain’s tolerance to temperature, pH, and solvents.

Proven Efficacy Through Scientific Testing

Gentle Exfoliation: In vitro microscopic imaging shows that 0.2% (w/v) Protesse G66 promotes keratin layer protein hydrolysis and reversibly restores the stratum corneum within 48 hours, demonstrating effective exfoliation without causing irritation.

Long-Lasting Hydration: In vivo testing reveals that a 5% Protesse G66 gel increases skin moisture by 13.9% after 8 hours, 19.5% after 24 hours, and 29.3% after 28 days.

Concentration-Dependent Cell Renewal: Ex vivo desquamation tests indicate that Protesse G66 enhances the removal of aged keratinocytes proportionally to concentration, improving skin brightness and texture.

Applications and Versatility
Protesse G66 is suitable for a wide range of formulations, including whitening creams, serums, essence waters, masks, and cleansers. Its stable and gentle profile makes it an ideal choice for high-performance, science-driven skincare products.

Conclusion
By combining papain with sclerotium gum in a controlled release matrix, Protesse G66 delivers effective exfoliation, improved skin texture, and long-lasting hydration while maintaining formulation stability. This innovative approach underscores the potential of encapsulation technology in modern skincare and provides brands with a reliable, versatile active for functional cosmetic applications.

Protesse G66


Post time: Jan-09-2026