ActiTide™ Bouncera represents a significant advancement in peptide-based cosmetic ingredients, offering a sophisticated anti-aging solution engineered to overcome the historical limitations of peptide bioavailability. While peptides are renowned for their biological signaling capabilities, their practical application is often constrained by high hydrophilicity and large molecular size, which hinder their ability to penetrate the skin’s lipid-rich stratum corneum. ActiTide™ Bouncera addresses these challenges by integrating a synergistic triple-peptide complex with groundbreaking delivery technology.
Overcoming Delivery Barriers with Supramolecular Technology
Traditional peptide formulations often suffer from poor transdermal absorption, resulting in active ingredients remaining on the skin’s surface without reaching the target dermal layers. ActiTide™ Bouncera solves this by utilizing Supramolecular Synergistic Penetration Technology, featuring DES-TG supramolecular ionic liquids.
This innovative approach creates a coordinated delivery system where the peptides—Palmitoyl Tripeptide-5, Hexapeptide-9, and Hexapeptide-11—are organized into a supramolecular complex. This technology modulates the skin barrier’s permeability in a controlled and “structure-friendly” manner, ensuring that the actives are efficiently driven into the deep epidermis and dermis without compromising the skin’s natural integrity.
Validated Penetration and Bioavailability
The technical superiority of ActiTide™ Bouncera is substantiated by rigorous in vitro skin penetration studies. Using advanced fluorescence tracer technology, the penetration properties of the individual peptides within the complex were evaluated. The study demonstrated that ActiTide™ Bouncera achieves a penetration intensity that is 3 to 5 times that of the control group for each individual peptide. Fluorescence imaging confirmed deep dermal targeting, ensuring that the biopeptide active ingredients reach the fibroblasts and the Dermal-Epidermal Junction (DEJ) where they can exert maximum effect.
Multi-Targeted Efficacy and Dermal Rebuilding
Beyond its superior delivery, ActiTide™ Bouncera exhibits profound bioactivity across multiple aging pathways in experimental studies:
DEJ Structural Support: It significantly upregulates the gene expression of Collagen IV and VII, critical proteins for strengthening the Dermal-Epidermal Junction and restoring the skin’s foundational support.
Collagen Synthesis: In efficacy tests, a concentration of just 0.15% promoted Type I Collagen synthesis by 332.32%, demonstrating a potent capacity for densifying the skin matrix and reducing wrinkle depth.
Inhibition of collagen degradation and collagen loss: It provides a strong defensive shield by inhibiting MMP-1 (the enzyme responsible for collagen degradation). At 0.10% concentration, MMP-1 levels were reduced by 94.66%, outperforming Vitamin C in comparative efficacy.
Physicochemical Properties and Applications
Physicochemically, ActiTide™ Bouncera is a colorless transparent to translucent liquid, designed for optimal stability and ease of formulation. It is highly compatible with a wide range of premium skincare products, including high-end serums, firming creams, and regenerative masks. The recommended dosage of 0.2–5.0% allows for versatile application in formulations targeting deep wrinkle reduction and structural skin rejuvenation.
In summary, ActiTide™ Bouncera embodies a technological leap from conventional peptide application to advanced biotechnological delivery. By combining the precision of a triple-peptide complex with the power of Supramolecular Synergistic Penetration, it provides a high-purity and high-performance solution for the next generation of professional skincare. Its demonstrated safety, deep-penetration capability (achieving 3-5 times the penetration of standard controls), and remarkable efficacy position it as a strategic ingredient for global cosmetic brands seeking scientifically validated results.
Post time: Jan-07-2026