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PromaCare^® R-PDRN represents a significant advancement in nucleic acid-based cosmetic ingredients, offering a recombinant salmon PDRN synthesized through biotechnology. Traditional PDRN is primarily extracted from salmon, a process constrained by high costs, batch-to-batch variability, and limited purity. Furthermore, reliance on natural resources poses environmental sustainability concerns and limits scalability to meet growing market demand. PromaCare^® R-PDRN addresses these challenges by utilizing engineered bacterial strains to replicate target PDRN fragments, enabling controlled synthesis while maintaining reproducible quality and minimizing ecological impact.